Thursday, October 23, 2008

Discolored nails



30 year old gentleman comes to the office stating “I have fungus on my nails”. He does not have any significant PMH and is currently not on any medications. He work involves cleaning dishes at a local restaurant. Review of systems is pertinent for red itchy skin rash behind both ears and in the inter-gluteal fold. As show in the picture, he has yellow discolored, pitted finger nails (and toe nails) with onycholysis and erythematous skin rash behind both the ears, with minimal scaling. A similar rash, without scaling is noted in the intergluteal fold extending up to the anal region.
Which of the following treatment options is most effective for his discolored nails?

A. Oral methotrexate
B. Topical methylprednisolone aceponate 0.1%- ANSWER
C. Oral Terbinafine
D. Topical Ciclopirox